ClinicalTrials.gov: heart disease | Recruiting, Not yet recruiting, Available Studies | First posted in the last 14 days

Studies found on ClinicalTrials.gov by a search of: heart disease | Recruiting, Not yet recruiting, Available Studies | First posted in the last 14 days

Study to Evaluate the QT / QTc Interval Prolongation Potential of Vericiguat

April 20, 2018

Condition:   Coronary Artery Disease
Interventions:   Drug: Vericiguat (BAY1021189);   Drug: Moxifloxacin;   Drug: Placebo
Sponsors:   Bayer;   Merck Sharp & Dohme Corp.
Not yet recruiting

Cardiac MRI for Optimal Heart Failure Outcomes With CRT Upgrades

April 20, 2018

Conditions:   Chronic Systolic Heart Failure;   Paroxysmal VT
Interventions:   Diagnostic Test: MRI prior to CRT Upgrade;   Diagnostic Test: MRI prior to de novo CRT
Sponsor:   University of Virginia
Recruiting

Same Day Subcutaneous ICD And Send Home (DASH)

April 20, 2018

Conditions:   Cardiomyopathies;   Cardiac Death, Sudden
Intervention:   Device: Subcutaneous ICD with same day discharge
Sponsors:   Emile Daoud, MD;   Boston Scientific Corporation
Recruiting

Synaptic Plasticity and Cognitive Function in RASopathies

April 20, 2018

Condition:   Noonan Syndrome, Neurofibromatosis Type 1
Interventions:   Drug: Lovastatin;   Drug: Lamotrigine
Sponsor:   Technische Universität München
Recruiting

Coronary Atherosclerosis T1-Weighted Characterization (CATCH)

April 20, 2018

Condition:   Coronary Atherosclerosis
Interventions:   Device: Cardiac MRI;   Drug: Contrast;   Drug: Beta blocker
Sponsor:   Cedars-Sinai Medical Center
Not yet recruiting

Effect of Trimetazidine on the Improvement of Coronary Microvascular Dysfunction in Patients With INOCA(Ischemia and no Obstructive Coronary Artery Disease)

April 20, 2018

Condition:   Patients With INOCA(Ischemia and no Obstructive Coronary Artery Disease) Who Have Coronary Microvascular Dysfunction
Intervention:   Drug: Trimetazidine
Sponsor:   Shanghai 10th People's Hospital
Not yet recruiting

Mitigating the Health Effects of Desert Dust Storms Using Exposure-Reduction Approaches

April 20, 2018

Conditions:   Asthma in Children;   Atrial Fibrillation
Interventions:   Behavioral: Intervention (1) for outdoor exposure reduction - Asthma in Children;   Behavioral: Intervention (2) for outdoor and indoor exposure reduction - Asthma in Children;   Behavioral: Intervention (1) for outdoor exposure reduction - Atrial Fibrillation;   Behavioral: Intervention (2) for outdoor and indoor exposure reduction - Atrial Fibrillation
Sponsors:   University of Cyprus;   University of Crete;   Soroka University Medical Center;   Cyprus University of Technology;   Cyprus Department of Labor Inspection;   Cyprus Department of Meteorology;   Cyprus Broadcasting Corporation;   E.n.A Consulting LP
Not yet recruiting

Noninferiority Trial of MitraClip Implantation Strategies: 1 Clip vs. 2 Clips in Patients With Functional Mitral Regurgitation

April 20, 2018

Condition:   Mitral Regurgitation Functional
Intervention:   Device: MitraClip implantation
Sponsors:   Asklepios proresearch;   Abbott
Not yet recruiting

The MitraClip® EXPAND Study

April 19, 2018

Conditions:   Mitral Valve Regurgitation;   Mitral Regurgitation
Intervention:   Device: MitraClip NTR/XTR System
Sponsors:   Evalve;   Abbott
Not yet recruiting

Cognitive Rehabilitation (Mega Team) and Its Effects on Emotional and Behavioral Regulation in ADHD, ASD, and CHD

April 18, 2018

Conditions:   ADHD;   ASD;   CHD - Congenital Heart Disease
Intervention:   Other: Mega Team - video game
Sponsors:   The Hospital for Sick Children;   SPOR CHILD-BRIGHT Network;   ehave;   The Governors of the University of Alberta
Not yet recruiting

Focused Cardiac Ultrasound in Surgery

April 18, 2018

Conditions:   Cardiopulmonary Disease;   Surgery;   Morality;   Complication
Intervention:   Diagnostic Test: FOCUS (focused cardiac ultrasound)
Sponsors:   Aarhus University Hospital;   Randers Regional Hospital;   Aabenraa Hospital
Not yet recruiting

The Effects of an Acute Bout of Exercise on Alcohol and Cocaine Craving - an fNIRS Study

April 18, 2018

Condition:   Substance Use Disorders
Interventions:   Other: Moderate exercise;   Other: Intense exercise;   Other: Reading
Sponsors:   University of Basel;   Psychiatric Hospital of the University of Basel
Recruiting

Heart Rate Variability and Cognitive Load on Image-Based Virtual Reality Instructional Design in Otolaryngology

April 18, 2018

Conditions:   Cognitive Function 1, Social;   Competence;   Heart Rate Fast;   Learning, Spatial;   Otolaryngologic Disorder
Interventions:   Other: image-based virtual reality learning;   Other: video-based learning
Sponsor:   Chang Gung Memorial Hospital
Not yet recruiting

Wireless Handheld 8-lead ECG Device Performance in Heart Patients (Rapid Rhythm)

April 18, 2018

Conditions:   Atrial Fibrillation;   Heart Murmurs
Intervention:   Device: Rapid Rhythm Handheld 8-lead ECG Device
Sponsors:   Manchester University NHS Foundation Trust;   Rapid Rhythm Ltd
Recruiting

Reducing Lung CongestIon Symptoms in Advanced Heart Failure

April 17, 2018

Condition:   Heart Failure
Interventions:   Device: V-Wave Interatrial Shunt;   Other: Control
Sponsor:   V-Wave Ltd
Not yet recruiting

Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes

April 17, 2018

Conditions:   Type2 Diabetes;   Insulin Resistance
Intervention:   Other: Acute exercise
Sponsors:   Odense University Hospital;   Department of Sports Science, University of Southern Denmark
Recruiting

Autoimmunity in the Pathogenesis of AF

April 17, 2018

Condition:   Atrial Fibrillation
Intervention:   Other: Peripheral Blood Sample
Sponsors:   Mayo Clinic;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

Effect of Evolocumab on Coronary Endothelial Function

April 17, 2018

Conditions:   Human Immunodeficiency Virus;   Coronary Artery Disease
Intervention:   Drug: evolocumab
Sponsor:   Johns Hopkins University
Not yet recruiting

Internet-delivered Cognitive Behaviour Therapy for Chronic Conditions: Comparing Low Intensity Delivery Models

April 17, 2018

Conditions:   Anxiety;   Depression;   Chronic Disease
Interventions:   Behavioral: Team-Guided ICBT;   Behavioral: Self-Guided ICBT
Sponsor:   University of Regina
Recruiting

Effects of Inspiratory Muscle and Endurance Training in Heart Failure Patients With Pacemaker

April 17, 2018

Condition:   Pacemaker
Interventions:   Device: Inspiratory muscle strength training;   Device: Inspiratory muscle endurance training
Sponsor:   Gazi University
Recruiting

MitraClip NT System Post-marketing Surveillance Study - Japan

April 17, 2018

Conditions:   Mitral Regurgitation;   Mitral Valve Regurgitation
Intervention:   Device: MitraClip NT System
Sponsors:   Evalve;   Abbott Vasular Japan Co., Ltd
Recruiting

A Clinical Trial on No-touch Vein Graft (NT-graft) in Coronary Surgery

April 17, 2018

Condition:   Ischemic Heart Disease
Interventions:   Procedure: No touch technique;   Procedure: Control technique
Sponsor:   Uppsala University
Not yet recruiting

Utility of the Cardiac Electrical BiomarkerDisease

April 13, 2018

Condition:   Acute Chest Syndrome
Intervention:  
Sponsor:   Bev Hoddell
Recruiting

Personal Decision Support System for Heart Failure Management

April 13, 2018

Condition:   Heart Failure, Congestive
Intervention:   Device: HeartMan system
Sponsors:   Jozef Stefan Institute;   University Ghent;   University of Roma La Sapienza
Recruiting

Beta Blocker Interruption After Uncomplicated Myocardial Infarction

April 13, 2018

Condition:   Myocardial Infarction
Interventions:   Drug: Beta-blockers withdrawal;   Drug: Continuation of the Betablockers (βB) treatment
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Action, France
Not yet recruiting

Half-normal Saline in Atrial Fibrillation Ablation

April 13, 2018

Condition:   Atrial Fibrillation
Interventions:   Drug: Half-normal saline;   Drug: Normal saline
Sponsor:   Texas Cardiac Arrhythmia Research Foundation
Not yet recruiting

Development and Progression of Carcinoid Heart Disease in a Cohort of Adult Patients With Neuroendocrine Tumors

April 13, 2018

Condition:   Carcinoid Heart Disease
Intervention:   Other: Study of the occurrence of Carcinoid Heart Disease
Sponsor:   Hospices Civils de Lyon
Not yet recruiting

Edwards SAPIEN 3 PPI Registry

April 13, 2018

Conditions:   Aortic Valve Stenosis;   AV Block;   Bundle-Branch Block
Intervention:   Procedure: transcatheter valve implantation
Sponsors:   Institut für Pharmakologie und Präventive Medizin;   Edwards Lifesciences
Not yet recruiting

Comparison of Pd/Pa Versus FFR in Intermediate Coronary Stenoses

April 13, 2018

Conditions:   Coronary Artery Disease;   Coronary Artery Stenoses
Interventions:   Diagnostic Test: measurement of FFR;   Diagnostic Test: measurement of Pd/Pa
Sponsors:   Leipzig Heart Institute GmbH;   Heartcenter Leipzig GmbH
Not yet recruiting

Hypothyroidism With Congenital Heart Disease (CHD)

April 12, 2018

Conditions:   Hypothyroidism;   CHD
Intervention:   Diagnostic Test: TSH , T4
Sponsor:   Assiut University
Not yet recruiting

Autologous Ovarian Tissue Transplantation

April 12, 2018

Conditions:   Primary Ovarian Insufficiency;   Female Infertility
Intervention:   Procedure: Ovarian tissue transplant
Sponsor:   University of Pittsburgh
Not yet recruiting

Atrial Fibrillation Cycle Length Measured on Transesophageal Echocardiography

April 12, 2018

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Pusan National University Yangsan Hospital
Recruiting

Extension Study of Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Previously Enrolled in PIONEER

April 12, 2018

Condition:   Hypertrophic Cardiomyopathy
Intervention:   Drug: mavacamten
Sponsor:   MyoKardia, Inc.
Not yet recruiting

CT Guided WiSE-CRT

April 12, 2018

Condition:   Heart Failure
Intervention:   Device: WiSE-CRT
Sponsors:   Guy's and St Thomas' NHS Foundation Trust;   National Institute for Health Research, United Kingdom
Not yet recruiting

Educational Intervention to Improve Patient-Physician Awareness of Cardiovascular Risk in Rheumatoid Arthritis.

April 12, 2018

Conditions:   Rheumatoid Arthritis;   Arthritis, Rheumatoid
Intervention:   Other: YouTube Video
Sponsors:   Rush University Medical Center;   Pfizer
Recruiting

Prehospital Translation of Chest Pain Tools

April 11, 2018

Conditions:   Acute Coronary Syndrome;   Pulmonary Embolism
Intervention:   Other: Data Collection
Sponsors:   Wake Forest University Health Sciences;   Cape Fear Valley Mobile Integrated Healthcare Cumberland County EMS;   New Hanover Regional Medical Center EMS
Recruiting

Bacteriological Link Between Upper and Lower Airways in Cystic Fibrosis and Primary Ciliary Dyskinesia

April 11, 2018

Conditions:   Cystic Fibrosis;   Primary Ciliary Dyskinesia
Intervention:   Other: Analysis with sequencing of the genotype of the bacteria
Sponsor:   Centre Hospitalier Intercommunal Creteil
Recruiting

Re-evaluation of Optimal Re-synchronisation Therapy in Patients With Chronic Heart Failure

April 11, 2018

Condition:   Chronic Heart Failure
Interventions:   Procedure: CRT-P implantation;   Procedure: CRT-D implantation
Sponsors:   Leipzig Heart Institute GmbH;   Heartcenter Leipzig GmbH
Not yet recruiting

Early Echographic Asystole as a Predictive Factor of Absence of Spontaneous Circulatory Activity Recovery (SCAR) in Prehospital Cardio Respiratory Arrests (CRA)

April 11, 2018

Conditions:   Prehospital Cardio-Respiratory Arrests;   Spontaneous Circulatory Activity Recovery
Intervention:   Other: Non applicable - Non interventional study
Sponsor:   Nantes University Hospital
Not yet recruiting

Heart Monitoring Device After Acute Myocardium Infarction

April 11, 2018

Condition:   Acute Myocardial Infarction
Interventions:   Device: Heart monitor;   Device: No heart monitor
Sponsor:   Instituto de Cardiologia do Rio Grande do Sul
Not yet recruiting

Prediction of ARrhythmic Events With Positron Emission Tomography II

April 10, 2018

Conditions:   Sudden Cardiac Arrest;   Ischemic Cardiomyopathy;   Congestive Heart Failure
Intervention:   Diagnostic Test: PET scan quantifying sympathetic denervation using [18F]-LMI1195
Sponsors:   State University of New York at Buffalo;   National Heart, Lung, and Blood Institute (NHLBI);   Lantheus Medical Imaging
Recruiting

Optimizing CRT With ECGI

April 10, 2018

Conditions:   Heart Failure, Systolic;   Left Bundle-Branch Block
Interventions:   Other: ECGI-optimized VV-offset;   Other: Zero VV-offset
Sponsors:   Washington University School of Medicine;   American College of Cardiology
Recruiting

Immune CHeckpoint Inhibitors Monitoring of Adverse Drug ReAction

April 10, 2018

Conditions:   Arthritis;   Cancer;   Cardiac Disease;   Endocrine System Diseases;   Autoimmune Diseases;   Ophthalmopathy;   Myositis;   Neuropathy
Intervention:   Drug: Immune checkpoint inhibitor
Sponsors:   Groupe Hospitalier Pitie-Salpetriere;   Institut National de la Santé Et de la Recherche Médicale, France
Recruiting

A Study for Comparison of Canagliflozin Versus Alternative Antihyperglycemic Treatments on Risk of Heart Failure Hospitalization and Amputation for Participants With Type 2 Diabetes Mellitus and the Subpopulation With Established Cardiovascular Disease

April 10, 2018

Conditions:   Diabetes Mellitus, Type 2;   Cardiovascular Diseases
Interventions:   Drug: Canagliflozin;   Drug: Empagliflozin;   Drug: Dapagliflozin;   Drug: Dipeptidyl Peptidase-4 (DPP-4) Inhibitors;   Drug: Glucagon-like Peptide-1 (GLP-1) Agonist;   Drug: Anti-hyperglycemic Agents (AHA);   Drug: Thiazolidinediones (TZD);   Drug: Sulfonylureas (SU);   Drug: Insulin
Sponsor:   Janssen Research & Development, LLC
Recruiting

Limb Girdle Muscular Dystrophy Type 2E Recruitment Study

April 10, 2018

Condition:   Limb-Girdle Muscular Dystrophy, Type 2E
Intervention:  
Sponsors:   Nationwide Children's Hospital;   Myonexus Therapeutics
Recruiting

Echocardiography During Ajmaline Test

April 09, 2018

Condition:   Brugada Syndrome
Intervention:   Drug: Ajmaline test
Sponsor:   Universitair Ziekenhuis Brussel
Recruiting

The Genetic Basis for Atrial Fibrillation

April 09, 2018

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Jesse Brown VA Medical Center
Recruiting

Clinical Study of Lipoic Acid on Ischemic Heart Failure

April 09, 2018

Condition:   Ischemic Heart Failure
Interventions:   Drug: Alpha-Lipoic Acid(α-LA);   Drug: Placebos
Sponsor:   Shanghai Zhongshan Hospital
Not yet recruiting

Free Iron and Out of Hospital Cardiac Arrest

April 09, 2018

Condition:   Arrest Cardio Respiratory
Intervention:  
Sponsor:   University Hospital, Brest
Not yet recruiting

Short and Fast Step Test: Feasibility, Validity and Tolerance of a Functional Evaluation Test of Lactic Anaerobic Capacities in Patients With Coronary Artery Disease

April 09, 2018

Condition:   Coronary Artery Disease Without Heart Failure
Interventions:   Other: Short and fast step test without measurement of pulmonary gas exchange;   Biological: glucose meter;   Other: ECG / heart rate;   Other: questionnaires;   Other: Short and fast step test with measurement of pulmonary gas exchange
Sponsor:   Centre Hospitalier Universitaire Dijon
Not yet recruiting

Patient and Family Partners in Heart Failure Care: Pilot Test of a Pre-visit Question Prompt List to Enhance Engagement During Medical Visits

April 09, 2018

Condition:   Heart Failure
Intervention:   Behavioral: Question/Topic Prompt List
Sponsors:   University of North Carolina, Chapel Hill;   RTI International
Not yet recruiting