ClinicalTrials.gov: heart disease | Recruiting, Not yet recruiting, Available Studies | Studies received in the last 14 days

Studies found on ClinicalTrials.gov by a search of: heart disease | Recruiting, Not yet recruiting, Available Studies | Studies received in the last 14 days

Immunotherapy With E6 T Cell Receptor (TCR) T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions

June 22, 2017

Conditions:   Human Papillomavirus;   HPV-16;   High Grade Squamous Intraepithelial Lesion
Interventions:   Drug: Aldesleukin;   Biological: E6 TCR
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting - verified June 15, 2017

Clinical Metagenomics of Infective Endocarditis

June 22, 2017

Condition:   Infective Endocarditis
Intervention:  
Sponsor:   University Hospital, Geneva
Recruiting - verified June 2017

Study to Evaluate Safety and Efficacy of Dapagliflozin and Saxagliptin in Patients With Type 2 Diabetes Mellitus Aged 10 to Below 18 Years Old

June 22, 2017

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Dapagliflozin;   Drug: Saxagliptin;   Drug: Placebo
Sponsor:   AstraZeneca
Not yet recruiting - verified June 2017

WFA+M2BP in Evaluation of Portal Hypertension and Clinical Outcome in Patients With Liver Cirrhosis

June 21, 2017

Conditions:   Portal Hypertension;   Cirrhosis
Intervention:   Drug: Carvedilol
Sponsors:   Shanghai Changzheng Hospital;   Shandong Provincial Hospital
Not yet recruiting - verified June 2017

Mindful Breathing Awareness Through Pursed-Lip Breathing Training

June 21, 2017

Condition:   Chronic Obstructive Pulmonary Disease
Intervention:   Other: Breathing Awareness
Sponsors:   Minnesota HealthSolutions;   Mayo Clinic
Not yet recruiting - verified June 2017

Critical Treatment of Coronary Artery Disease

June 21, 2017

Conditions:   Coronary Artery Disease;   Coronary Artery Disease Progression
Intervention:   Device: Stent implantation
Sponsors:   Southeast University, China;   Science and Technology Department of Jiangsu Province
Recruiting - verified June 2017

Empagliflozin in Heart Failure Patients With Reduced Ejection Fraction

June 21, 2017

Condition:   Heart Failure With Reduced Ejection Fraction
Interventions:   Drug: Empagliflozin 10 MG;   Other: Placebo
Sponsor:   Morten Schou
Not yet recruiting - verified June 2017

Bexagliflozin Drug/Drug Interaction Study With Digoxin

June 21, 2017

Condition:   Type2 Diabetes Mellitus
Interventions:   Drug: Bexagliflozin;   Drug: Digoxin
Sponsor:   Theracos
Not yet recruiting - verified June 2017

Characterization of Heart Failure With Preserved Ejection Fraction

June 20, 2017

Condition:   Fibrosis Estimated by cMR Ant Biomarkers
Interventions:   Diagnostic Test: cMR;   Biological: biomarker
Sponsor:   Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Recruiting - verified June 2017

Adherence to ASV Therapy in Heart Failure With Preserved Ejection Fraction Feasibility Study

June 20, 2017

Conditions:   Heart Failure With Normal Ejection Fraction;   Sleep Apnea
Intervention:   Device: ASV Therapy
Sponsor:   ResMed
Not yet recruiting - verified June 2017

Retrospective Data Analysis of Data From the Zurich PH Registry

June 20, 2017

Conditions:   Pulmonary Hypertension;   Chronic Thromboembolic Pulmonary Hypertension;   Pulmonary Artery Hypertension
Intervention:  
Sponsor:   University of Zurich
Recruiting - verified June 2017

The Effect of Liposomal Bupivacaine on Post Operative Pain and Narcotic Use After Bariatric Surgery

June 20, 2017

Conditions:   Bariatric Surgery Candidate;   Pain, Postoperative
Interventions:   Drug: Exparel 266 MG Per 20 ML Injection;   Drug: Bupivacaine
Sponsor:   University of California, San Francisco
Not yet recruiting - verified June 2017

Rhythmic Reading Training Compared to 'Abilmente' Method

June 20, 2017

Condition:   Developmental Dyslexia
Interventions:   Behavioral: RRT+sat;   Behavioral: Abilmente
Sponsor:   Catholic University of the Sacred Heart
Recruiting - verified June 2017

Safety and Efficacy of Low Dosage of Terazosin in Subjects Undergoing Carotid Artery Stenting

June 20, 2017

Condition:   Carotid Artery Stenosis
Interventions:   Drug: Terazosin;   Procedure: Carotid artery stenting
Sponsor:   Capital Medical University
Not yet recruiting - verified June 2017

Effect of Normobaric Hypoxia and Hyperoxia in Patients With Pulmonary Hypertension

June 20, 2017

Condition:   Pulmonary Hypertension
Intervention:   Other: Hypoxia and Hyperoxia
Sponsor:   University of Zurich
Recruiting - verified June 2017

Corazon de la Familia (Heart of the Family)

June 20, 2017

Conditions:   Risk Reduction Behavior;   Diabetes Mellitus, Type 2;   Cardiovascular Diseases
Interventions:   Behavioral: Family-focused intervention arm;   Behavioral: Individual-focused intervention arm
Sponsors:   University of Kentucky;   National Institute of Nursing Research (NINR);   National Institutes of Health (NIH)
Not yet recruiting - verified June 2017

Impact of Perioperative Shedding of the Endothelial Glycocalyx on the Incidence of Postoperative Acute Kidney Injury in Patients Undergoing Valvular Heart Surgery.

June 20, 2017

Condition:   Valvular Heart Disease
Intervention:  
Sponsor:   Yonsei University
Not yet recruiting - verified June 2017

Water Intake Associated With Aerobic Exercise in Coronary

June 19, 2017

Condition:   Coronary Artery Disease
Interventions:   Other: Water intake;   Other: Treadmill aerobic exercise
Sponsor:   Universidade Estadual Paulista Júlio de Mesquita Filho
Not yet recruiting - verified June 2017

PARTNER 3 Trial - Mitral Valve in Valve

June 19, 2017

Conditions:   Mitral Valve Insufficiency;   Mitral Valve Disease;   Mitral Valve Regurgitation;   Heart Failure
Intervention:   Device: Edwards SAPIEN 3 transcatheter valve, Model 9600TFX
Sponsor:   Edwards Lifesciences
Not yet recruiting - verified June 2017

Mono- Versus Dual antiPlatelet Therapy During 6-12 Months After New Generation Drug Eluting Stent Implantation

June 19, 2017

Conditions:   Gastrointestinal Injury;   Ischemic Heart Disease
Interventions:   Drug: Aspirin + clopidogrel;   Drug: Clopidogrel monotherapy;   Drug: Aspirin monotherapy
Sponsors:   Shenyang Northern Hospital;   Changhai Hospital;   ANKON medical technologies (Shanghai)Co.,LTD
Not yet recruiting - verified June 2017

Real World Registry Assessing the Clinical Use of the Bard UltraScore Forced Focus PTA Balloon

June 19, 2017

Conditions:   Peripheral Arterial Disease;   Peripheral Vascular Diseases;   Arterial Occlusive Diseases
Intervention:   Device: PTA (UltraScore Focused Force PTA Balloon)
Sponsor:   C. R. Bard
Not yet recruiting - verified June 2017

A Trial Testing Amiodarone in Chagas Cardiomiopathy

June 19, 2017

Condition:   Chagas Cardiomyopathy
Interventions:   Drug: Amiodarone Hydrochloride;   Drug: Placebo Oral Tablet
Sponsors:   Fundación Cardioinfantil Instituto de Cardiología;   Instituto de Corazón de Bucaramanga
Recruiting - verified June 2017

Observational Study for Feasibility and Performance of Sub-millisievert Coronary Computed Tomography Angiography (CCTA) for Coronary Artery Anomalies (CAA) in Paediatric Patients

June 19, 2017

Condition:   Coronary Artery Anomaly, Congenital
Intervention:   Diagnostic Test: coronary angiography
Sponsor:   University Hospital, Montpellier
Not yet recruiting - verified June 2017

Native T1 Mapping by Cardiovascular Magnetic Resonance Imaging in Rare Diseases

June 19, 2017

Condition:   Fabry Disease
Intervention:  
Sponsors:   University College, London;   University Hospital Birmingham;   University of Sydney
Recruiting - verified June 2017

The Prospective Segeberg TAVI Registry

June 18, 2017

Condition:   Aortic Valve Stenosis
Intervention:   Device: Transcatheter Aortic Valve Implantation
Sponsor:   Herz-Kreislauf-Zentrum Segeberger Kliniken GmbH
Recruiting - verified June 2017

Efficacy and Safety of Berberine in Non-alcoholic Steatohepatitis

June 18, 2017

Condition:   Non-alcoholic Steatohepatitis
Interventions:   Behavioral: Lifestyle intervention;   Drug: Placebo;   Drug: Berberine
Sponsors:   Fudan University;   Shanghai Jiao Tong University Affiliated Sixth People’s Hospital;   Xinhua Hospital, Shanghai Jiao Tong University School of Medicine;   The Affiliated Hospital of Hangzhou Normal University;   Tianjin Third Central Hospital;   Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine;   Xinjiang Medical University
Not yet recruiting - verified June 2017

Cardiac Arrest Registry of the Province of Pavia (Pavia CARe)

June 17, 2017

Condition:   Out-Of-Hospital Cardiac Arrest
Intervention:  
Sponsors:   IRCCS Policlinico S. Matteo;   Azienda Regionale Emergenza Urgenza - AREU Lombardia;   Azienda Socio-Sanitaria Territoriale di Pavia
Recruiting - verified June 2017

T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery

June 16, 2017

Conditions:   Breast Cancer;   Brain Metastasis;   Brain Cancer
Interventions:   Drug: T-DM1;   Drug: TMZ
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting - verified June 13, 2017

The FAVOR II China Study

June 16, 2017

Conditions:   Coronary Artery Disease;   Myocardial Ischemia;   Cardiovascular Diseases;   Arteriosclerosis;   Coronary Disease;   Arterial Occlusive Diseases;   Heart Diseases;   Vascular Diseases
Intervention:   Diagnostic Test: Fractional Flow Reserve (FFR)
Sponsors:   China National Center for Cardiovascular Diseases;   Pulse Medical Imaging Technology (Shanghai) Co., Ltd
Recruiting - verified June 2017

Research Study Comparing a New Medicine Semaglutide to Liraglutide in People With Type 2 Diabetes

June 16, 2017

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: Semaglutide;   Drug: Liraglutide
Sponsor:   Novo Nordisk A/S
Not yet recruiting - verified June 2017

Study of High Efficient Killing Cell Therapy for Advanced NSCLC

June 16, 2017

Condition:   Non Small Cell Lung Cancer
Intervention:   Biological: HEKT cell
Sponsors:   Ruijin Hospital;   Shanghai Houchao Biotechnology Co., Ltd
Not yet recruiting - verified June 2017

AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke

June 16, 2017

Condition:   Stroke
Interventions:   Drug: Apixaban;   Drug: Aspirin
Sponsors:   Columbia University;   National Institute of Neurological Disorders and Stroke (NINDS);   University of Cincinnati;   Medical University of South Carolina;   Bristol-Myers Squibb;   Pfizer;   Roche Pharma AG
Not yet recruiting - verified June 2017

Effect of Isocaloric Ultra Processed Versus Unprocessed Diets on Insulin Sensitivity

June 15, 2017

Condition:   Obesity
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting - verified May 30, 2017

Effects of Canagliflozin on Intravascular Volume and Hemodynamics

June 15, 2017

Conditions:   Type2 Diabetes Mellitus;   Cardiovascular Diseases
Interventions:   Drug: Canagliflozin 300mg;   Drug: Placebo
Sponsors:   Devjit Tripathy;   Janssen Scientific Affairs, LLC
Not yet recruiting - verified June 2017

CES1 Carriers in the PAPI Study

June 14, 2017

Conditions:   Heart Diseases;   Coronary Disease;   Coronary Artery Disease;   Cardiovascular Diseases;   Myocardial Ischemia;   Artery Occlusion;   Aspirin Sensitivity;   Clopidogrel, Poor Metabolism of;   Platelet Dysfunction;   Platelet Thrombus
Interventions:   Drug: Clopidogrel;   Drug: Aspirin
Sponsor:   University of Maryland
Not yet recruiting - verified June 2017

Study on Registration of Xinyuan Capsule

June 14, 2017

Condition:   Coronary Disease
Intervention:  
Sponsors:   China Academy of Chinese Medical Sciences;   Xiyuan Hospital of China Academy of Chinese Medical Sciences
Not yet recruiting - verified June 2017

A Registry Study on Safety Surveillance of Dazhuhongjingtian (a Chinese Medicine Injection) Used in China

June 14, 2017

Condition:   Coronary Heart Disease
Intervention:   Other: a cohort using Dazhuhongjingtian injection
Sponsors:   China Academy of Chinese Medical Sciences;   Hospital of Changchun University of Traditional Chinese Medicine
Not yet recruiting - verified June 2017

Combined Upper-airway and Breathing Control Therapies for Obstructive Sleep Apnea

June 14, 2017

Condition:   Obstructive Sleep Apnea
Interventions:   Device: Oral appliance;   Drug: Oxygen;   Other: Oral appliance plus oxygen;   Other: No treatment
Sponsors:   Brigham and Women's Hospital;   Monash University;   American Heart Association;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified June 2017

The Effect of Neprilysin (LCZ696) on Exercise Tolerance in Patients With Heart Failure

June 14, 2017

Conditions:   Heart Failure;   Exercise Tolerance;   Vasodilation;   Body Composition;   Muscle Strength
Interventions:   Drug: Neprilysin;   Drug: Enalapril
Sponsor:   University of Sao Paulo General Hospital
Recruiting - verified June 2017

Noninvasive Ventilation Therapy for the Treatment of Pleural Effusion in Patients With Heart Failure

June 14, 2017

Conditions:   Pleural Effusion;   Heart Failure
Intervention:   Device: Non-invasive ventilation
Sponsors:   Heart and Diabetes Center North-Rhine Westfalia;   ResMed GmbH & Co KG
Not yet recruiting - verified June 2017

Aerobic Exercise in Women With Systemic Lupus Erythematosus

June 13, 2017

Conditions:   Systemic Lupus Erythematosus;   Lupus;   Autoimmune Disease;   Rheumatic Disease
Intervention:   Other: Treadmill exercise training
Sponsor:   National Institutes of Health Clinical Center (CC)
Not yet recruiting - verified June 2, 2017

AMCPR (Augmented-Medication CardioPulmonary Resuscitation) Trial for OHCA

June 13, 2017

Condition:   Out-of-Hospital Cardiac Arrest
Interventions:   Drug: Vasopressins;   Drug: Normal saline
Sponsor:   Asan Medical Center
Not yet recruiting - verified June 2017

A Study of PEG-somatropin Injection to Treat Children of Turner Syndrome

June 13, 2017

Condition:   Turner Syndrome
Interventions:   Biological: PEG-rhGH low dose;   Biological: PEG-rhGH high dose;   Other: Non-treatment control group
Sponsors:   GeneScience Pharmaceuticals Co., Ltd.;   Beijing Children's Hospital;   The First Affiliated Hospital with Nanjing Medical University;   Shanghai Children's Hospital;   Children's Hospital of Fudan University;   Xinhua Hospital, Shanghai Jiao Tong University School of Medicine;   First Hospital of Jilin University;   Jiangxi Province Children's Hospital;   Affiliated Hospital of Jiangnan University;   The Children's Hospital of Zhejiang University School of Medicine
Recruiting - verified June 2017

IRIS-BioFreedom Cohort in the IRIS-DES Registry

June 13, 2017

Condition:   Coronary Stenosis
Intervention:   Device: BioFreedom stent
Sponsors:   Duk-Woo Park;   CardioVascular Research Foundation, Korea
Not yet recruiting - verified June 2017

CORonary MICrovascular Angina (CorMicA)

June 13, 2017

Conditions:   Angina, Stable;   Coronary Vasospasm;   Coronary Circulation;   Coronary Syndrome;   Microvascular Angina;   Coronary Disease
Intervention:   Diagnostic Test: Stratified medicine involving a diagnostic intervention
Sponsors:   NHS National Waiting Times Centre Board;   British Heart Foundation
Recruiting - verified June 2017

Autologous Bronchial Basal Cell Transplantation for Treatment of COPD

June 13, 2017

Condition:   Chronic Obstructive Pulmonary Disease
Intervention:   Biological: Bronchial basal cells
Sponsors:   Regend Therapeutics;   Southwest Hospital, China;   Tongji University
Recruiting - verified June 2017

A PATH (Promoting Activity and Trajectories of Health) for Children

June 13, 2017

Conditions:   Motor Performance;   Physical Activity
Intervention:   Behavioral: Motor Skills Intervention
Sponsors:   University of Michigan;   National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting - verified June 2017

Clinical Trial of Cilostazol Eluting Stent System (CES-1) in De Novo Coronary Artery Lesions

June 13, 2017

Condition:   Coronary Artery Disease
Intervention:   Device: Cilostazol eluting stent system (CES-1)
Sponsor:   JIMRO Co., Ltd.
Recruiting - verified June 2017

Compared With 2 Different Ablation Strategies Clinical Outcome for Treating Patients With Paroxysmal Atrial Fibrillation

June 13, 2017

Condition:   Paroxysmal Atrial Fibrillation
Interventions:   Procedure: CPVI Group;   Procedure: CPVI+LARA Group
Sponsors:   Zhujiang Hospital;   Nanfang Hospital of Southern Medical University
Recruiting - verified September 2016

Ultrasound Assessment of Volume in Patients on Continuous Dialysis

June 13, 2017

Conditions:   Volume Overload;   Kidney Failure;   Respiratory Failure
Interventions:   Other: Share ultrasound measurement of IVC collapsibility to Nephrology Attending;   Other: Do not share ultrasound measurement of IVC collapsibility to Nephrology Attending
Sponsor:   University of Alabama at Birmingham
Recruiting - verified June 2017

Patients' Assessment of Satisfaction for Stroke Prevention in Atrial Fibrillation

June 13, 2017

Condition:   Atrial Fibrillation
Intervention:   Drug: Pradaxa®
Sponsor:   Boehringer Ingelheim
Not yet recruiting - verified June 2017

Fractional Flow Reserve Derived From Computed Tomography Coronary Angiography in the Assessment and Management of Stable Chest Pain

June 13, 2017

Condition:   Coronary Artery Disease
Interventions:   Diagnostic Test: FFRct;   Diagnostic Test: Standard care
Sponsor:   University Hospital Southampton NHS Foundation Trust
Not yet recruiting - verified June 2017

A Prospective Study on the Long-Term Vascular Burden in TTP Patients

June 13, 2017

Condition:   Thrombotic Thrombocytopenic Purpura
Interventions:   Diagnostic Test: CT Perfusion Study;   Diagnostic Test: Echocardiogram
Sponsor:   Lawson Health Research Institute
Recruiting - verified January 2017

Acute Mental Stress During Lumbar Puncture

June 13, 2017

Conditions:   Stress, Emotional;   Spinal; Puncture, Complications, Headache;   Lumbar Puncture
Intervention:  
Sponsors:   Rigshospitalet, Denmark;   Region Zealand
Recruiting - verified June 2017

Comparison of Diagnostic and Therapeutic Efficacy of EBUS-TBNA/EUS-FNA and TEMLA in Operable NSCLC. A Randomised Controlled Trial

June 13, 2017

Condition:   Non-small Cell Lung Cancer
Interventions:   Other: PET/CT;   Procedure: EBUS-TBNA, EUS-NA;   Procedure: TEMLA
Sponsor:   Pulmonary Hospital Zakopane
Recruiting - verified June 2017

Heart Failure Study of Multi-site Pacing Effects on Ventriculoarterial Coupling

June 12, 2017

Condition:   Heart Failure
Intervention:   Device: Activation of multi-site pacing capability on CRT devices
Sponsor:   National and Kapodistrian University of Athens
Not yet recruiting - verified June 2017

Heart Failure and Sudden Cardiac Death Japan Registry

June 12, 2017

Conditions:   Heart Failure;   Arrhythmias, Cardiac;   Sudden Cardiac Death
Interventions:   Device: CRT-D;   Device: ICD;   Device: PM / CRT-P;   Other: Non-device
Sponsors:   Boston Scientific Corporation;   ICON Clinical Research
Not yet recruiting - verified June 2017

Phase-I Trial of Pembrolizumab and Percutaneous Cryoablation Combination Followed by Nephron-Sparing Surgery or Cytoreductive Nephrectomy in Locally Advanced and Metastatic Renal Cell Carcinomas

June 12, 2017

Conditions:   Renal Cell Carcinoma;   Metastatic Kidney Cancer
Interventions:   Drug: Pembrolizumab Injection [Keytruda];   Procedure: Cryoablation;   Procedure: Nephrectomy
Sponsor:   University of California, Irvine
Recruiting - verified June 2017

CardioTOxicity Induced by andRogeNICS and Their Antagonists (TORNICS)

June 12, 2017

Condition:   Heart Diseases
Intervention:   Drug: Hormonal therapies: G03, H01C and L02 in the ATC classification
Sponsor:   Groupe Hospitalier Pitie-Salpetriere
Recruiting - verified June 2017

Effects of Respiratory Muscle Training on Respiratory Muscle Strength, Functional Capacity and Quality of Life in Pulmonary Hypertension

June 12, 2017

Condition:   Respiratory Muscle Strength
Intervention:   Other: respiratory muscle training
Sponsor:   Faculdade de Ciências Médicas da Santa Casa de São Paulo
Not yet recruiting - verified June 2017

REDUCE LAP-HF III Corvia Protocol 1701

June 12, 2017

Condition:   Heart Failure
Intervention:   Device: IASD Implant
Sponsor:   Corvia Medical
Not yet recruiting - verified June 2017